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Cough is a familiar and protective reflex for all of us. Even when we are feeling healthy, most of us will cough as a way of clearing our throat or preventing food and fluid from entering our airways and lungs, or simply from the shock of breathing in cold air.6,7 Unfortunately, a cough can become a nuisance when it is frequent or chronic and interferes with everyday life.8,9



Sinusitis occurs when the mucous lining of the sinuses becomes inflamed (swollen) and starts to produce extra mucus, which is often thick.2,10 The inflammation and excess mucus block the sinuses10,11 and interfere with the functioning of the cilia.12


ACC 200

ACC 200 contains an active ingredient called N-acetylcysteine (NAC).1 NAC acts directly on the thick mucus in the respiratory airways,13,14 breaking down the bonds that hold the mucus together. Clearing the thick, sticky mucus stuck in your airways may also help prevent a new or different infection developing there.15,16 ACC 200 is an over-the-counter (OTC) medication that you can buy at a pharmacy, without a prescription.1 

  1. ACC 200 approved package insert, April 2013.
  2. Helms S and Miller A. Natural treatment of chronic rhinosinusitis. Altern Med Rev. 2006; 11(3):196-207.
  3. Rogers DF. Concoctive agents for airway mucus hypersecretory diseases. Respir Care 2007; 52(9):1176-1193.
  4. Database of medicine prices [internet]. South African Medicine Price Registry ©2010. Last updated: 21 Dec 2018. Available from Last accessed 28 Feb 2019.
  5. IMS Data (Sales volume) – R05CB Market. MAT Dec 2018.
  6. Eccles R and Mallefet P. Soothing properties of glycerol in cough syrups for acute cough due to common cold. Pharmacy 2017; 5(1)4.
  7. Chung KF. Management of cough. In: Chung KF et al. Cough: Causes, mechanisms and therapy 2003; Chapter 27:283-297.
  8. Morice AH et al. Recommendations for the management of cough in adults. Thorax 2006; 61 Suppl 1:i1-24.
  9. Chung KF. The clinical and pathophysiological challenge of cough. In: Chung KF et al. Cough: Causes, mechanisms and therapy 2003; Chapter 1:3-10.
  10. Ah-See KW and Evans AS. Sinusitis and its management. BMJ 2007; 334:358-361.
  11. BMJ Best Practice. Acute sinusitus. Last updated: 01 Mar 2019. Available at: Last accessed May 2019.
  12. Hallet R and Naguwa SM. Severe rhinosinusitis. Clin Rev Allergy Immunol 2003; 25:177-190.
  13. Kryukov A.I., et al. Treatment of Acute Sinusitis. Russian Medical Journal. Otorhinolaryngology, 2012, No. 9, pp. 485-488.
  14. Zaitseva OV. Rational choice of mucolytic therapy in treatment of respiratory diseases in children. RMJ. 2009; 17(19):1217-1221.
  15. Mutie M. Acute and chronic cough presentations in pharmacy. Pharmacy Education Jun 2014; 65-67.
  16. Knowles MR and Boucher RC. Mucus clearance as a primary innate defense mechanism for mammalian airways. J Clin Invest  2002; 109(5):571-577.