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ACC 200 is an over-the-counter (OTC) medication that you can buy at a pharmacy.1 ACC 200 is a mucolytic, which means that it is a medication that breaks down or disrupts mucus.1,2 In South Africa, it is available as an effervescent tablet that dissolves in water.1
ACC 200 contains an active ingredient called N-acetylcysteine (NAC).1 NAC acts directly on thick and sticky mucus in the respiratory airways,3,4 breaking down the bonds that hold the mucus together. It does this without significantly increasing the quantity of mucus or fluid in the airways.4
NAC’s action thins thick mucus quickly, and makes it less sticky,4,5 so that the runnier, more liquid mucus is easier to blow, sneeze or cough out of the airways.3,4 NAC has been shown to improve the rate at which mucus clears from the airways by 35%.6
NAC thins thick, sticky phlegm (a form of mucus produced by the lower airways) quickly and makes it more liquid so that it is easier to clear from the lungs.4,5
NAC has been shown to reduce coughing within 4 – 5 days of starting treatment.4
Clearing the thick, sticky mucus stuck in your airways may also help to prevent a new or different infection developing there.7,8
Because NAC thins thick, sticky mucus quickly and makes it more liquid, it becomes easier to clear the mucus from the nasal passages and sinuses.6 Clearing mucus from the sinuses improves the oxygenation and airflow in this area,9 which reduces sinus congestion and decreases its associated pain and pressure.3
Most patients report a decrease in sinus discomfort and ‘heaviness’ in the first days after starting treatment with NAC.3
Clearing the thick, sticky mucus stuck in your sinuses may also help to prevent a new or different infection developing there.7,8
ACC 200 is a registered medication by the South African Health Products Regulatory Authority (SAHPRA) in South Africa.1 It is a Schedule 1 medication, which means you can buy it from any pharmacy which stocks OTC medications.1 Your doctor may also prescribe it for you.
ACC 200 is manufactured by Sandoz (a division of Novartis). ACC 200 has been available on the South African market for over 20 years.1
You can use it for up to 14 days.1 If you would like to use it for longer than 14 days, please consult your doctor.1
ACC 200 has no known harmful interactions with other medications,1 but please do check with your doctor or pharmacist about whether it may interact with medications you are taking.
When taking an antibiotic, you should allow at least a two-hour interval between taking the antibiotic and taking ACC 200, so that both medications can work well.1
Remember that most acute coughs and sinusitis are caused by a virus11,12 and that antibiotics do not help to treat viruses.13
In South Africa, ACC 200 is approved for use in children from the age of two years.1
The effervescent tablet should be dissolved in a glass of water before use.
If you suffer from any of the following, please consult your pharmacist or doctor before taking ACC 200: