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GET COUGH RELIEF WITH ACC®

Is your family struggling with chesty, wet coughs?

ACC® can help!1(p1),2(p1),3(p1218),4(p130),5(p751),6(p127,130)

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YOU COUGH, ACC® RELIEF

Coughing is one of the most common reasons that people seek medical advice.7(p5) It’s triggered by irritation in the airways, which can be caused by an underlying condition like a cold or respiratory infection.7(p5) A wet (productive) cough is a type of cough caused by too much mucus in your airways.8(p732)

 

What is mucus? Mucus is a slippery liquid substance produced by your body.9(p1) When it’s produced in normal amounts, it helps to keep your tissues hydrated and to prevent infection.9(p1) However, the mucus your body produces when you’re sick is thicker and stickier than normal.9(p1) Large amounts of this sticky stuff can clog up your airways and make you cough.8(p732),9(p1)

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TREATING A COUGH WITH ACC®

ACC® contains an active ingredient called acetylcysteine (uh-see-tuhl-sisteen).1(p1),2(p1),10 This ingredient breaks down the bonds that hold thick, sticky mucus together, so the mucus becomes thinner.1(p1),2(p1),5(p751),6(p127,130) This makes it easier for you to cough it out and clear your airways, giving you the relief that you need.1(p1),2(p1),3(p1218)

Acetylcysteine is absorbed quickly, which means ACC® gets to work fast to offer relief from coughs.4(p130)

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Did you know? Clearing excess phlegm from your lungs can also prevent a more serious infection from developing there.11(p1)

HOW DOES ACC® WORK?

ACC® is a type of medication known as a mucolytic.1(p1),2(p1),4(p130),6(p127,130) This means ACC® breaks down mucus to make it easier to clear out of your chest.1(p1),2(p1),3(p1218) It’s also a mucoregulator, which means it helps to regulate (control) mucus secretion.4(p130)

THE ACC® PRODUCT RANGE

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Speak to your healthcare provider about ACC® today and find out which option is right for you.

  • ACC® Long (600 mg effervescent tablets): Fizzy tablets for adults or adolescents aged 14 and up1(p1)

  • ACC® 200 POS (200 mg powder for oral solution): Sachets of soluble powder for adults or children aged 6 and up2(p1)

didyouknow

Note: Consult your doctor before taking a pharmaceutical product.

For more information, click to download the ACC® product package leaflets.

 

References

1. Hexal AG. ACC long 600 mg (effervescent tablets). Patient information. February 2020.

2. Hexal AG. ACC 200 mg (powder for oral solution). Patient information. January 2020.

3. Zaitseva OV. Rational choice of mucolytic therapy in treatment of respiratory diseases in children. Russian Medical Journal. 2009;17(19):1217-1221.

4. Sadowska AM. N-Acetylcysteine mucolysis in the management of chronic obstructive pulmonary disease. Ther Adv Respir Dis. 2012;6(3):127-135.

5. Aldini G, Altomare A, Baron G, et al. N-acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why. Free Radical Research. 2018;52(7):751-762.

6. Balsamo R, Lanata L, Egan CG. Mucoactive drugs. Eur Respir Rev. 2010 Jun;19(116):127-133.

7. Chung KF, Widdicombe JG, Boushey HA. Cough: causes, mechanisms and therapy. 2003; Chapter 1:3-10.

8. Murata A, Taniguchi Y, Hashimoto Y, et al. Discrimination of productive and non-productive cough by sound analysis. Intern Med. 1998;37:732-735.

9. What is mucus? Learn how to get rid of it. MedicineNet. Accessed May 29, 2022. https://www.medicinenet.com/what_is_mucus/article.htm.

10. How to pronounce acetylcysteine - Google search. Accessed June 10, 2021. https://www.google.com/search?q=how+to+pronounce+acetylcysteine&rlz=1C1LOQA_enZA752ZA760&oq=how+to+pronounce+acetylceistine&aqs=chrome.

11. Knowles MR, Boucher RC. Mucus clearance as a primary innate defense mechanism for mammalian airways. J Clin Invest. 2002;109(5):571-577.

 
PRESENTATION: ACC® 200 mg: One Sachet with 3 g powder contains 200 mg acetylcysteine. ACC® long: One effervescent tablet contains 600 mg acetylcysteine. INDICATION: ACC 200 & ACC long: contains the active substance acetylcysteine and liquefies viscous mucus in the airways. ACC 200 mg powder for oral solution is used to loosen mucus and to ease coughing up in cases of respiratory diseases with viscous mucus in children from 6 years, adolescents and adults. ACC long is used to loosen mucus and to ease coughing up in cases of cold –induced bronchitis in adolescents over 14 years of age and adults. DOSAGE: ACC 200: Children and adolescents from 6-13 years: 1 sachet 2 times daily. Adults and adolescents aged 14 years and older: 1 sachet 2-3 times daily. Treatment of mucoviscidosis in children aged over 6 years: 1 sachet 3 times daily. ACC long: For adults and adolescents over the age of 14 year, ½ effervescent tablet twice daily or 1 effervescent tablet once daily. OVERDOSING: ACC 200 & ACC long : Irritations in the stomach and bowel tract may occur, such as abdominal pain, nausea, vomiting, diarrhoea. if an overdose is suspected, please inform your doctor CONTRAINDICATIONS: ACC 200 & ACC long :allergic to acetylcysteine, or any of the ingredients of this medicine. ACC 200: children under 2 years of age, children under 6 years of age. ACC long: children and adolescent under 14 years. PRECAUTIONS/WARNINGS: ACC 200& ACC long: Caution is advised if you have bronchial asthma and a history of stomach or bowel ulcers or currently have them, patients with hypersensitivity to histamine. An inability to cough up mucous. If skin and mucosal changes newly occur, medical advice should be sought without delay and use of acetylcysteine be terminated. INTERACTIONS: ACC 200 & ACC long: Antibiotics ,tetracyclines, aminoglycosides, penicillins, Cough-relieving agents, Activated charcoal ,Nitroglycerin. ACC long: carbamazepine. Pregnancy and lactation: ACC 200 & ACC long: you should use ACC long during pregnancy and lactation only if your attending physician considers this absolutely necessary. Take ACC 200 or ACC long after meals. ACC 200 & ACC long is not known to influence the ability to drive or operate machines. SIDE EFFECTS: ACC Long: Two serious side effects are the severe skin reactions such as Stevens-Johnson syndrome (painful red or purplish rash that spreads and blisters) and / or Lyell Syndrome (mucosal lesions only or both mucosal and skin lesions including bubble formations). They have been reported in temporal association with the use of acetylcysteine. In most of these reported cases, at least one additional drug that could potentially have intensified the described mucocutaneous effects was being taken at the same time. If skin or mucous membrane abnormalities develop, medical advice should therefore immediately be sought and the use of acetylcysteine discontinued. PHARMACEUTICAL PRECAUTIONS: ACC 200 & ACC Long: Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the sachet and the carton after EXP.The expiry date refers to the last day of that month. ACC 200: Store Below 25°C, in a dry place, ACC long: Do not store above 25°C. keep the tube tightly closed in order to protect from moisture. NOTE: Before prescribing, please read full prescribing information. REFERENCE: ACC 200: Approved PIL, revision date January 2020. ACC long: Approved PIL, revision date February 2020. BSS DATE: June 2021

 

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